The body has a natural biological clock that knows when he should be active or resting. Someone needs to follow biological rhythms in order to stay healthy, because disturbances in the biological clock may increase the risk of type 2 diabetes.
Researchers from Vanderbilt University in Nashville trying to learn whether the biological clock disorders greatly affect a person's health. The study involved two groups of mice, where the first group had a normal biological clock, while the second group bred genetic defect by inactivating the biological clock.
Researchers measured the difference between the activity of insulin and body weight in each group of mice. In rats disturbed biological clock, researchers found that there were changes in insulin activity cycle throughout the day.
Mice were able to control insulin properly when he is on, but if the mouse is active at too much of the day and led to lack of time off, can lead to insulin resistance. This suggests that a person's biological rhythms play an important role in the regulation of insulin.
Mice that have been damaged due to interference with the biological clock can even get stuck in the mode of insulin resistance over a period of 24 hours. Insulin is a hormone that regulates blood sugar, and insulin resistance occurs when the body is no longer effective in lowering blood glucose in response to insulin.
Insulin resistance is a major marker of type 2 diabetes. This finding adds to the evidence that animal and human biological clock disorders, such as changes in sleep cycles may increase the risk of obesity and type 2 diabetes.
"Most studies observed insulin activity in rats during daylight hours only, whereas this study to monitor the activity of insulin throughout the day to determine the terms of the biological clock disorders," said Carl Johnson, PhD, lead author of the study.
Researchers are also studying the long-term effects of the biological clock disorders. Both groups of mice were fed fatty foods for two months.
After two months, the researchers weigh the mice in each group and it is known that both have almost the same weight. However, mice that had been broken biological clock have more fatty deposits on the body than the control mice.
These findings also apply to people who are not able to keep the biological clock, an increased risk of type 2 diabetes and obesity. Biological clock disorders common in people who work with the system of shift work or frequent travelers experience jet lag due to travel a lot on a regular basis.
Research shows that the shift of sleep in night shift workers, making it more susceptible to some diseases related to obesity, such as metabolic syndrome and type 2 diabetes. This relationship may be due to disturbance of the biological clock affects the body's circadian rhythms, regulation of blood sugar and metabolism.
All you need to do to avoid these risks is to improve the body's biological clock. Make sure that you get enough hours of sleep and quality. Turn off all electronic equipment and Dim the room lights when you go to bed.