Fat Women are More Vulnerable to Endometrial Cancer

Endometrial cancer usually occurs in women who have menopause. Recent studies have shown that the risk may be increased if you are overweight or obese.

"Fat tissue is a major source of circulating estrogen in menopausal women. Estrogen is to promote the development of endometrial cancer," said Victoria L. Stevens, the leader of the study and a director of the National Home Office of the American Cancer Society in Atlanta.

In the study, researchers analyzed the Stevens team health data of more than 38,000 postmenopausal women who completed the survey in 1992. In 2007, 560 women involved in the study had been diagnosed with endometrial cancer.

After adjusting for body mass index (BMI) of each participant, the study showed that women who were overweight by 30 pounds or more, have a chance of developing endometrial cancer by 2-fold compared to women with normal weight.

While this study only found that weight gain after menopause associated with the risk of endometrial cancer and does not show a causal relationship.

"Women who have menopause weight gain should be prevented to reduce the risk of endometrial cancer. If you have been overweight before menopause, lose weight quickly to prevent the risk," said Stevens.

The researchers state that further research is still needed to decide whether the time of weight gain and yo-yo dieting (weight loss in a super fast, but weight loss can also back up quickly if not maintained properly) is also linked to cancer risk endometrium.

The research findings were presented at the event ACR International Conference on Frontiers in Cancer Prevention Research in Boston, as reported by Every Day Health, Tuesday (05/02/2013).


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